HA Fillers

Facial filler or dermal fillers are gels used for the purpose of filling up an area with lost volume. The lost volume could be from loss of deep or superficial fat or loss of collagen and hydration from the skin it self, which makes the overlying skin loose, hanging, wrinkled, thin and lack of glow. Broadly the fillers can be categorized as Hyaluronic acid like restylane/juvederm/versa/bolletero, collagen generating like sculptra aesthetics/Bellafill and calcium based Radiesse. Hyaluronic acid (HA) Filler and Radiesse are discussed here. 

Hyaluronic Acid (HA) Fillers

HA is a normal constituent of the skin and deeper tissue, which primarily gives the firm, full and radiant appearance of the skin. HA in the skin and soft tissues are metabolized very quickly and half life is about a day in the skin and a few mins in the soft tissues. A major part of the skin aging depends on how quick the metabolism is and the final content in the skin. HA fillers have special side links which holds strands of the HA polymers together and thus increase the life of the polymers in the skin. Depending on the amount of the side links and process used to create makes these gels firmer or softer, elastic or particulate, shorter or longer lasting, more or less swelling. These characteristics are used in deciding the type of the HA filler for use of rejuvenation of the tissue. Below major HA fillers will be discussed. 

Restylane Group of Fillers

Restylane group of fillers are made by major pharmaceutical company Galderma. The fillers in this group are Restylane lyft, Restylane-L, Restylane Silk, Restylane Refyne and Restylane Defyne.

Restylane Silk 

Finally, a filler that can help you achieve your ideal lips. Restylane® Silk is the first FDA-approved product specifically designed for lip augmentation and the smoothing of wrinkles around the mouth in patients 21 years of age and older.

Restylane Lyft

Help complete your aesthetic look with natural-looking volume in your cheeks and hands for a smoother, fuller appearance. Restylane® Lyft is a safe, effective and dissolvable HA filler. Treatment can be administered in your hands and face at the same appointment — and can result in a more youthful-looking appearance.


Restylane® can be used to add volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane may also be used for lip enhancement.

Restylane Refyne

Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions.1-4 So, you always look like you. Talk to your specialist and see for yourself why it’s worth it.

Restylane Defyne

Crafted with XpresHAn Technology™, Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.


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